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Psychodermatology: The Mind and Skin Connection

American Family Physician,  Dec 1, 2001  by John Koo,  Andrew Lebwohl

A psychodermatologic disorder is a condition that involves an interaction between the mind and the skin. Psychodermatologic disorders fall into three categories: psychophysiologic disorders, primary psychiatric disorders and secondary psychiatric disorders. Psychophysiologic disorders (e.g., psoriasis and eczema) are associated with skin problems that are not directly connected to the mind but that react to emotional states, such as stress. Primary psychiatric disorders involve psychiatric conditions that result in self-induced cutaneous manifestations, such as trichotillomania and delusions of parasitosis. Secondary psychiatric disorders are associated with disfiguring skin disorders. The disfigurement results in psychologic problems, such as decreased self-esteem, depression or social phobia. Most psychodermatologic disorders can be treated with anxiety-decreasing techniques or, in extreme cases, psychotropic medications. (Am Fam Physician 2001;64:1873-8. Copyright[C] 2001 American Academy of Family Physicians.)

Psychodermatology, or psychocutaneous medicine, focuses on the boundary between psychiatry and dermatology. Understanding the psychosocial and occupational context of skin diseases is critical to the optimal management of psychodermatologic disorders.

The management of psychodermatologic disorders requires evaluation of the skin manifestation and the social, familial and occupational issues underlying the problem. Once the disorder has been diagnosed, management requires a dual approach, addressing both dermatologic and psychologic aspects. Even with self-induced skin problems, supportive dermatologic care is needed to avoid secondary complications, such as infection, and to ensure that the patient feels supported. Patients with psychodermatologic disorders frequently resist referral to mental health professionals. Acceptance of psychiatric treatment or consultation may be enhanced through support from the family physician.

Management options include psychotropic medication, stress management courses and referral to a psychiatrist. Family physicians are well positioned to help patients with psychodermatologic disorders; these patients may be concerned about the stigma associated with psychiatrists, and family physicians are familiar with the use of psychotropic medications.

Classification

Psychodermatologic disorders can be broadly classified into three categories: psychophysiologic disorders, primary psychiatric disorders and secondary psychiatric disorders.(1) The term "psychophysiologic disorder" refers to a skin disorder, such as eczema or psoriasis, that is worsened by emotional stress (Figure 1). "Primary psychiatric disorder" refers to a skin disorder such as trichotillomania, in which the primary problem is psychologic; the skin manifestations are self-induced. "Secondary psychiatric disorders" affect patients with significant psychologic problems that have a profoundly negative impact on their self-esteem and body image. Depression, humiliation, frustration and social phobia may develop as a consequence of a disfiguring skin disorder.(2) Table 1 lists common diagnoses associated with the different categories of psychodermatologic disorders.

TABLE 1

Diagnoses Associated
with Psychodermatologic Disorders

Major categories         Examples

Psychophysiologic        Acne
  disorders              Alopecia areata
                         Atopic dermatitis
                         Psoriasis
                         Psychogenic purpura
                         Rosacea
                         Seborrheic dermatitis
                         Urticaria (hives)

Primary psychiatric      Bromosiderophobia
  disorders              Delusions of parasitosis
                         Dysmorphophobia
                         Factitial dermatitis
                         Neurotic excoriations
                         Trichotillomania

Secondary psychiatric    Alopecia areata
  disorders              Cystic acne
                         Hemangiomas
                         Ichthyosis
                         Kaposi's sarcoma
                         Psoriasis
                         Vitiligo

Psychophysiologic Disorders

Psychophysiologic disorders are conditions that are frequently precipitated or exacerbated by emotional stress. Each of these conditions has "stress responders" and "non-stress responders," depending on whether a patient's skin disease is or is not frequently and predictably exacerbated by stress. The proportion of stress responders depends on the dermatologic diagnosis involved, as illustrated in Table 2.(3)

In patients with treatment-responsive skin conditions such as eczema, psoriasis and acne, the issue of stress may not be important.(4) However, when physicians are faced with disease recalcitrant to treatment, patients should be asked whether psychologic, social or occupational stress might be contributing to the skin disorder.

Emotional stress may exacerbate many chronic dermatoses and can initiate a vicious cycle referred to as the "itch-scratch cycle"; therefore, treatment of recalcitrant patients with chronic dermatoses may be difficult without addressing stress as an exacerbating factor.(5) Patients often are embarrassed about discussing psychologic issues, especially if they feel hurried. Stress management classes, relaxation techniques, music or exercise may benefit these patients. If a specific psychosocial or occupational issue exists, therapy or counseling can help.