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Encyclopedia of Medicine by Nancy Ross-Flanigan
Interactions
MAO inhibitors may interact with many other medicines. When this happens, the effects of one or both of the drugs may change or the risk of side effects may be greater. Anyone who takes MAO inhibitors must check with his or her physician before taking any other prescription or nonprescription (over-the-counter) medicine. Among the drugs that may interact with MAO inhibitors are:
- Central nervous system (CNS) depressants such as medicine for allergies, colds, hay fever, and asthma; sedatives; tranquilizers; prescription pain medicine; muscle relaxants; medicine for seizures; sleep aids; barbiturates; and anesthetics.
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- Medicine for high blood pressure
- Other antidepressants, including tricyclic antidepressants (such as Tofranil and Norpramin), antidepressants that raise serotonin levels (such as Prozac and Zoloft), and bupropion (Wellbutrin)
- Diabetes medicines taken by mouth
- Insulin
- Water pills (diuretics).
The list above does not include every drug that may interact with MAO inhibitors. Check with a physician or pharmacist before combining MAO inhibitors with any other prescription or nonprescription (over-the-counter) medicine.
Key Terms
- Anxiety
- Worry or tension in response to real or imagined stress, danger, or dreaded situations. Physical reactions, such as fast pulse, sweating, trembling, fatigue, and weakness may accompany anxiety.
- Central nervous system
- The brain and spinal cord.
- Depression
- A mental condition in which people feel extremely sad and lose interest in life. People with depression may also have sleep problems and loss of appetite and may have trouble concentrating and carrying out everyday activities.
- Neurotransmitter
- A chemical that carries messages from one nerve cell to another.
- Phobia
- An intense, abnormal, or illogical fear of something specific, such as heights or open spaces.
- Withdrawal symptoms
- A group of physical or mental symptoms that may occur when a person suddenly stops using a drug to which he or she has become dependent.
Further Reading
Gale Encyclopedia of Medicine. Gale Research, 1999.
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